Course Catalog

Program Name: Biomedical Sciences
Course Name: Embryos Genes and Development Course Id: 2301
Course Description:

This course will provide a thorough introduction to invertebrate and vertebrate development emphasizing cellular, genetic and molecular mechanisms. The course will focus primarily on development of fruit flies, nematodes, Xenopus, zebrafish, and mice. Emphasis will be on understanding fundamental embryological processes such as induction, determination, and pattern formation. Current technologiessuch as transgenic animals, genetics, mosaic analysis, homologous recombination, somatic cell genetics, and classical embryonic manipulations will be analyzed. Selected topics include developmental genetics of regulatory hierarchies, lateral inhibition, regeneration and development, cell lineage analysis, X-chromosome inactivation, imprinting, and sex determination. Following introductory lectures, the course will focus on primary literature detailing the current state of the field using journal club presentation (by students). The final exam will consist of grant proposals by the students tobe reviewed by other students in a study section type arrangement

Credits: 3
Semester Offered: Fall

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