Name: Aleyasin, Hossein
Year you started at ISMMS: 2013
Lab: Dr. Scott Russo
Lab Mailing Address:
1425 Madison Ave.- Room 10-02, New York, NY, 10029
Cellular and molecular mechanisms of neuroplasticity in response to stress.
Previous Postdoc Experience:
I received my MD from Tehran University of Medical Sciences, Tehran, Iran and my PhD in neuroscience from the University of Ottawa, Ontario, Canada. I studied the role of a Parkinson’s disease (PD) associated gene, DJ-1 (PARK7) and showed the neuroprotective activity of DJ-1 in models of PD and stroke. For the first time I demonstrated the essential role that DJ-1 plays in protecting neurons in oxidative stress. Moreover, I found that this activity is partially through activation of AKT signaling pathway. for my first postdoc, I studied the neuroprotective role of hypoxia inducible factor (HIF) mediated by drugs that bind to tubulin at Burke/Cornell Medical Research Institute in White Plains, NY.
Pubmed Feed: Click Here
Collaborations and Other Affiliations:
Interested in understanding the role of intracellular hydrogen peroxide (H2O2), and in collaboration with my colleagues at Burke, Dr. Chang, dep. of Chemistry at UC, Berkeley, and Dr. Xu at school of applied engineering and physics, Cornell University, developed tools to enzymatically produce and monitor the amount of this messenger/toxin within its dynamic range. These tools are essential to study the role of intracellular H2O2 in physiological and pathological conditions.
Funding Sources and Prizes/Awards
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