Student Profiles

Name: Browne, Andrew
Year you started at ISMMS: 2011
Program: PhD      MTA: NEU

 

Why you chose ISMMS?

I chose ISMMS because of the extremely collaborative research environment both between researchers and with clinicians as well. The available of clinical data and the ability to translate research into real treatments is something ISMMS strongly encourages.

Lab: Dr. Joseph Buxbaum

Project:

I am generating stem cells from the blood of patients with Phelan-McDermid Syndrome, a monogenic syndrome very commonly associated with autism, and reprogramming these cells into neural cell types for characterization and candidate drug identification through the use of RNA sequencing.

Undergrad institution and major: Brown University, B.S. in Neuroscience

What did you do between college and grad school?

I was a technician in the laboratory of Dr. Rudolph Tanzi at Mass General Hospital in Boston, MA from 2008 to 2010 where I studied Alzheimer’s disease by knocking down candidate genes and testing potential therapeutics in human neuroglioma and neuroblastoma cell lines for their ability to modulate amyloid precursor protein processing.

From 2010 to 2011 I worked in the lab of Dr. Lorraine Clark studied the genetics of Parkinson’s disease where I focused on high-throughput genotyping of patient samples and mapping of insertion and deletion breakpoints in the LRRK2 gene.

What do you like to do outside of school?

I enjoy spending time with my wife (and soon my daughter!), listening to and occasionally playing music, lifting weights, computer gaming, rock climbing, paintball, scuba diving, travel, pets (I have 2 pet rats).

What is your favorite quote? It’s better to beg for forgiveness than to ask for permission.

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