Student Profiles

Name: Craig, Amanda
Year you started at ISMMS: 2011
Program: PhD      MTA: CAB


Why you chose ISMMS?

I chose ISMMS for the collaborative environment and access to resources necessary for translational research.

Lab: Augusto Villanueva


HCC is a highly heterogeneous cancer at the morphological level. We aim to understand the underlying molecular pathways and mechanisms that lead to this heterogeneity. We will do this by taking a comprehensive approach involving sequencing of multiple regions of a tumor as well as isolated single cells. By analyzing mutation status, copy number alterations, RNA expression and methylation levels we will be able to map the evolution of sub-clonal populations in a single tumor as well as identify the various deregulated pathways involved in tumor initiation and maintenance. The goal of this project is to help us understand the accuracy of single biopsies as well as drug resistance in HCC.

Undergrad institution and major: Rutgers University, Biotechnology B.S

What did you do between college and grad school?

Worked as a research technician at Memorial Sloan-Kettering Cancer Center

What do you like to do outside of school?

Play recreational softball and volleyball

What is your favorite quote?

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